CRISPR

After just a few weeks of growth, flowers on poplar trees can be seen in the lab. These flowers typically don’t appear until after seven years of tree growth. (Photo by C.J. Tsai)
Shrinking the breeding experiments with trees from years to weeks with CRISPR
After just a few weeks of growth, flowers on poplar trees can be seen in
Microglia (green) derived from human stem cells by members of the Kampmann lab. Image by Olivia Teter, Kampmann lab, UCSF
The opportunity for an entirely new type of therapeutic approach to treat Alzheimer’s and other forms of dementia
Microglia (green) derived from human stem cells by members of the Kampmann lab. Image by
Restorative gene editing using sequences from the counterpart chromosome: The standard CRISPR enzyme Cas9 offers the ability to make repairs but also potentially results in unintended mutations (mutagenic events) at the targeted site and possibly elsewhere in the genome (left). In contrast, the nickase enzyme results in more efficient gene correction and no mutagenic events (right).
A new and safer CRISPR approach that may correct genetic defects in the future
Restorative gene editing using sequences from the counterpart chromosome: The standard CRISPR enzyme Cas9 offers
CRISPR 3.0: Gene activation instead of traditional gene editing
via Phys.org CRISPR 3.0: Gene activation instead of traditional gene editing Multiplexed gene activation system
New approach to gene therapy can correct any disease-causing mutation within a gene
A new approach to gene editing, developed by Penn State researchres, using the CRISPR/Cas9 system
Curing sickle cell disease with CRISPR technology
via Ash Image Bank This blood smear shows sickle cell disease. Curing sickle cell disease
A new way of dramatically speeding up production of innovative bio-based fuels, materials, and chemicals
Study authors (from left to right) Andrew K. Lau, Thomas Eng, and Deepanwita Banerjee stand
A therapeutically safer strategy for CRISPR gene editing
Mutating the enzyme at the heart of the CRISPR gene editing system can improve its
CRISPR can be a conservation and resource management tool to help endangered species
Longfin smelt can be difficult to differentiate from endangered Delta smelt. Here, a longfin smelt
Glaucoma could be successfully treated with a single injection using gene therapy
Histological section of a ciliary body.  Credit: University of Bristol Glaucoma could be successfully treated
New tool for probing the human genome and RNA viruses like coronavirus and flu
Computer model of a single-molecule magnet New tool for probing the human genome and RNA
Slowing the progression of ALS using CRISPR – in mice
CRISPR base editing decreased the amount of a mutant protein (blue) that contributes to ALS
The success of gene editing and cell function offers new hope to cancer patients
via University of Pennsylvania The success of gene editing and cell function offers new hope
Using DNA to delete disease
DNA is obscured by closed chromatin, an innately protective structure made up of proteins that
A good system for delivering biological medicines straight to the inside of a cell?

Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can