Washington University School of Medicine (WUSM), located in St. Louis, Missouri, is the medical school of Washington University in St. Louis on the eastern border of Forest Park in St. Louis
MRI brain scans can predict with 89 percent accuracy who will go on to develop dementia within three years
One day, MRI brain scans may help predict whether older people will develop dementia, new research suggests. In a small study, MRI brain scans predicted with 89 percent accuracy who would go on to develop dementia within three years, according to research at Washington University School of Medicine in St. Louis and the University of
New ALS therapy extends survival and reverses some neuromuscular damage in animals
Drug extends survival, reverses some neuromuscular damage in animals About 20,000 people in the United States are living with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. The invariably fatal disease kills the nerve cells that control walking, eating and breathing. Few people survive more than three years after diagnosis. Now, new research
Cardiovascular medicine is being transformed by virtual reality
Developments could lead to lower costs, better outcomes Rapid advancements in the field of virtual reality are leading to new developments in cardiovascular treatment and improved outcomes for patients, according to a review paper published today in JACC: Basic to Translational Science. Extended reality applications in cardiac care include education and training, pre-procedural planning, visualization
Can noninvasive radiation treatment help a deadly heart rhythm problem?
Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis have shown that radiation therapy — aimed directly at the heart — can be used to treat patients with a life-threatening heart rhythm. They treated five patients who had irregular heart rhythms, called ventricular tachycardia,
Assessing a disease that effects 120 million people worldwide with a portable 3-D scanner
Device measures swollen limbs faster, more easily than other methods An estimated 120 million people worldwide are infected with lymphatic filariasis, a parasitic, mosquito-borne disease that can cause major swelling and deformity of the legs, a condition known as elephantiasis. Health-care workers rely on leg measurements to assess the severity of the condition. However, measuring
Motor neurons created directly from human skin cells
New technique could aid treatments for diseases that lead to paralysis Scientists working to develop new treatments for neurodegenerative diseases have been stymied by the inability to grow human motor neurons in the lab. Motor neurons drive muscle contractions, and their damage underlies devastating diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy, both
A blood test for Alzheimer’s?
Decades before people with Alzheimer’s disease develop memory loss and confusion, their brains become dotted with plaques made of a sticky protein – called amyloid beta – that is thought to contribute to the disease and its progression. Currently, the only way to detect amyloid beta in the brain is via PET scanning, which is
An antibody that ‘neutralizes’ the Zika virus?
Researchers at Vanderbilt University Medical Center and Washington University School of Medicine in St. Louis have isolated a human monoclonal antibody that in a mouse model “markedly reduced” infection by the Zika virus. The antibody, called ZIKV-117, also protected the fetus in pregnant mice infected with the virus, the researchers reported today in the journal
NMN reduces signs of aging: It’s safety is being tested
Safety of NMN being tested in small clinical trial in Japan Much of human health hinges on how well the body manufactures and uses energy. For reasons that remain unclear, cells’ ability to produce energy declines with age, prompting scientists to suspect that the steady loss of efficiency in the body’s energy supply chain is
Grow a living hip replacement and fight arthritis as well
Technique uses 3-D weaving to grow a living hip replacement With a goal of treating worn, arthritic hips without extensive surgery to replace them, scientists have programmed stem cells to grow new cartilage on a 3-D template shaped like the ball of a hip joint. What’s more, using gene therapy, they have activated the new
As more states legalize marijuana, adolescents’ problems with pot decline
Fewer adolescents also report using marijuana A survey of more than 216,000 adolescents from all 50 states indicates the number of teens with marijuana-related problems is declining. Similarly, the rates of marijuana use by young people are falling despite the fact more U.S. states are legalizing or decriminalizing marijuana use and the number of adults
Stem cells from diabetic patients coaxed to become insulin-secreting cells
If damaged cells are replaceable, type 1 diabetics wouldn’t need insulin shots Signaling a potential new approach to treating diabetes, researchers at Washington University School of Medicine in St. Louis and Harvard University have produced insulin-secreting cells from stem cells derived from patients with type 1 diabetes. People with this form of diabetes can’t make
Light — not pain-killing drugs — used to activate brain’s opioid receptors
Despite the abuse potential of opioid drugs, they have long been the best option for patients suffering from severe pain. The drugs interact with receptors on brain cells to tamp down the body’s pain response. But now, neuroscientists at Washington University School of Medicine in St. Louis have found a way to activate opioid receptors with
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