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University of California San Diego School of Medicine

University of California San Diego School of Medicine

The University of California San Diego School of Medicine is the graduate medical school of the University of California San Diego in La Jolla, California.

Do artificial neural networks need “sleep” in order to do better?

Wastewater screening could provide early detection of Covid-19 to stop outbreaks

On the brink of new hope for pancreatic cancer?

One-time treatment eliminates Parkinson’s disease and regrows neurons: in mice

Microbial DNA may reveal who has cancer and which type even at early stages

DNA fingerprints could catch cancer-causing culprits

The eyes may prove to be another valuable tool to diagnose Alzheimer’s

Researchers say how quickly a person’s pupil dilates while taking cognitive tests Alzheimer’s disease (AD) begins to alter and damage the brain years — even decades — before symptoms appear, making early identification of AD risk paramount to slowing its progression. In a new study published online in the September 9, 2019 issue of the Neurobiology

The eyes may prove to be another valuable tool to diagnose Alzheimer’s

Eliminating damaged mitochondria alleviates chronic inflammatory disease – in mice

Treatment with a choline kinase inhibitor prompts immune cells to clear away damaged mitochondria, thus reducing NLRP3 inflammasome activation and preventing inflammation Inflammation is a balanced physiological response – the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases. To help

Eliminating damaged mitochondria alleviates chronic inflammatory disease – in mice

New strategies to target pancreatic cancer

Researchers discover unexpected role of an immune system receptor; blocking it halts human cancer cell growth and improves survival in animal models For some cancers, initial treatment with chemotherapy brings positive, but only temporary, results: tumors shrink, but then rebound as the cancer becomes drug-resistant. This pattern of remission-resistance-relapse is particularly true for pancreatic cancer,

New strategies to target pancreatic cancer

Promoting nerve cell growth to treat spinal cord injury with a 3D printed implant

In rat models, the novel scaffolding mimicked natural anatomy and boosted stem cell-based treatment; the approach is scalable to humans and advances effort toward clinical trials For the first time, researchers at University of California San Diego School of Medicine and Institute of Engineering in Medicine have used rapid 3D printing technologies to create a

Promoting nerve cell growth to treat spinal cord injury with a 3D printed implant

Sensors that detect and measure cancer’s ability to spread

The spread of invasive cancer cells from a tumor’s original site to distant parts of the body is known as metastasis. It is the leading cause of death in people with cancer. In a paper published online in iScience , University of California San Diego School of Medicine researchers reported engineering sensors that can detect and measure

Sensors that detect and measure cancer’s ability to spread

A potential new approach for preventing or reversing a number of inflammatory diseases

Study uncovers new potential therapeutic approach for a number of diseases linked to inflammation, including atherosclerosis, aortic stenosis and hepatic steatosis Researchers at University of California San Diego School of Medicine discovered that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids (OxPL), molecules on cell surfaces that get

A potential new approach for preventing or reversing a number of inflammatory diseases

A major and essential step toward future human clinical trials to repair spinal cord injuries

Findings represent major and essential step toward future human clinical trials Led by researchers at University of California San Diego School of Medicine, a diverse team of neuroscientists and surgeons successfully grafted human neural progenitor cells into rhesus monkeys with spinal cord injuries. The grafts not only survived, but grew hundreds of thousands of human

A major and essential step toward future human clinical trials to repair spinal cord injuries

A potential new approach to autism utilizing a 100 year old drug called suramin

Small, randomized clinical trial reported measurable, but transient, benefits after single dose of suramin, highlighting novel causative theory and need for more, larger and longer trials In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat

A potential new approach to autism utilizing a 100 year old drug called suramin

Molecular Switch Controlling Immune Suppression May Help Turn Up Immunotherapies

Discovery could broaden effectiveness of emerging therapies for cancer and other diseases that are based on boosting the natural immune system response Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to maximize the effectiveness of anti-cancer immune therapy. The researchers identified  a molecular switch that

Molecular Switch Controlling Immune Suppression May Help Turn Up Immunotherapies

How to Erase a Memory – And Restore It

  Researchers at the University of California, San Diego School of Medicine have erased and reactivated memories in rats, profoundly altering the animals’ reaction to past events. The study, published in the June 1 advanced online issue of the journal Nature, is the first to show the ability to selectively remove a memory and predictably reactivate

How to Erase a Memory – And Restore It

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