Tag: new antibiotics
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Breakthrough: Overcoming gram-negative bacterial defenses
Scientists report that they now know how to build a molecular Trojan horse that can penetrate gram-negative bacteria, solving a problem that for decades has stalled the development of effective new antibiotics against these increasingly drug-resistant microbes. The findings appear in the journal Nature. Led by University of Illinois chemistry professor Paul Hergenrother, the scientists…
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New antibiotics produced from fungi show promise
Fungi is a potential goldmine for the production of pharmaceuticals. This is shown by Chalmers researchers, who have developed a method for finding new antibiotics from nature’s own resources. The findings could prove very useful in the battle against antibiotic resistance. ?Antibiotics have saved millions of lives since they were discovered in the 1940s. But…
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“Flipping the switch” reveals new compounds with antibiotic potential
Many fungi have antibacterial properties. Researchers at Oregon State University have discovered that one gene in a common fungus acts as a master regulator, and deleting it has opened access to a wealth of new compounds that have never before been studied – with the potential to identify new antibiotics. The finding was announced today…
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Biologists Discover New Method for Discovering Antibiotics
Promises to revolutionize how drug discovery teams guide their studies Biologists at the University of California, San Diego have developed a revolutionary new method for identifying and characterizing antibiotics, an advance that could lead to the discovery of new antibiotics to treat antibiotic resistant bacteria. The researchers, who published their findings in this week’s early…
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A shot in the arm for old antibiotics
Low doses of silver make bacteria more susceptible to antibiotic attack, paving the way for new therapies for drug-resistant and recurrent infections Slipping bacteria some silver could give old antibiotics new life, scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University reported June 19 in Science Translational Medicine. Treating bacteria with a…
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Key to New Antibiotics Could Be Deep Within Isolated Cave
Could mean good news in the battle against superbugs Antibiotic-resistant bacteria found in one of the deepest, most isolated caves in the world could mean good news in the battle against superbugs. Researchers from McMaster and the University of Akron have discovered a remarkable prevalence of such bacteria in New Mexico’s Lechuguilla Cave, a place…
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New Antibiotics?
Solving Mystery of How Sulfa Drugs Kill Bacteria Yields 21st Century Drug Development Target St. Jude Children’s Research Hospital scientists have discovered a key enzyme structure in bacteria, a finding that lays the foundation for a new generation of antibiotics that are safer and less prone to drug resistance. More than 70 years after…
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Scientists Hope to Cut Years Off Development Time of New Antibiotics
Eliminating tens of thousands of manual lab experiments, two University of Houston (UH) professors are working toward a method to cut the development time of new antibiotics. While current practices typically last for more than a decade, a computerized modeling system being developed at UH will speed up this process. Vincent Tam, associate professor of…