Oregon Health & Science University (OHSU) is a public university in Oregon with a main campus, including two hospitals, in Portland.
A new approach to diagnosis and treatment for rare diseases that cumulatively affect millions
Better definition could lead to better diagnosis and treatment for rare diseases that cumulatively affect millions Thousands of rare diseases cumulatively affect millions of people across the globe, yet because each case is so rare doctors struggle to accurately diagnose and effectively treat individual patients. Every time a patient with an unspecified disorder walks into
Using biological enzymes as an efficient source of hydrogen fuel
Research from the University of Illinois and the University of California, Davis has chemists one step closer to recreating nature’s most efficient machinery for generating hydrogen gas. This new development may help clear the path for the hydrogen fuel industry to move into a larger role in the global push toward more environmentally friendly energy
New computational method could help diagnose and rectify a genetic defect with gene-editing tools
Technique could help diagnose, rectify a genetic defect with gene-editing tools such as CRISPR Scientists have devised a new computational method that reveals genetic patterns in the massive jumble of individual cells in the body. The discovery, published in the journal eLife, will be useful in discerning patterns of gene expression across many kinds of disease, including
Researchers collaborate on potential game-changer for people with multiple sclerosis
Study shows promise in repairing damaged myelin A scientific breakthrough provides new hope for millions of people living with multiple sclerosis. Researchers at OHSU have developed a compound that stimulates repair of the protective sheath that covers nerve cells in the brain and spinal cord. The discovery, involving mice genetically engineered to mimic multiple sclerosis, published
A new target to prevent and treat alcoholism
New research conducted at OHSU in Portland, Oregon, identifies a gene that could provide a new target for developing medication to prevent and treat alcoholism. Scientists at the Oregon National Primate Research Center at OHSU discovered a gene that had lower expression in the brains of nonhuman primates that voluntarily consumed heavy amounts of alcohol
A drug compound that stops cancer cells from spreading throughout the body
Via a mouse model, OHSU physician-scientists lead effort to hone a drug that inhibits cancer cells from spreading to other areas in the body Fighting cancer means killing cancer cells. However, oncologists know that it’s also important to halt the movement of cancer cells before they spread throughout the body. New research, published today in
Medicinal properties of cannabis could provide non-addictive pain relief
Journal of Neuroscience study examines medicinal properties of cannabis OHSU research suggests an avenue for developing treatments for chronic pain that harness the medicinal properties of cannabis while minimizing the threat of addiction. The study, conducted in a rodent model, provides additional rationale for the development of therapeutics using cannabinoid receptors to treat chronic pain,
Magnetic pulses to the brain deliver long-lasting relief for tinnitus patients
Depression treatment tool holds tremendous promise for patients with debilitating condition In the largest U.S. clinical trial of its kind funded by the Veterans Affairs (VA) Rehabilitation Research and Development Service, researchers at the VA Portland Medical Center and Oregon Health & Science University found that transcranial magnetic stimulation significantly improved tinnitus symptoms for more
Antioxidant drug knocks down multiple sclerosis-like disease in mice
“These results are really exciting. This could be a new front in the fight against MS.” Researchers at Oregon Health & Science University have discovered that an antioxidant designed by scientists more than a dozen years ago to fight damage within human cells significantly helps symptoms in mice that have a multiple sclerosis-like disease. The
OHSU researchers develop new drug approach that could lead to cures for wide range of diseases
A team led by a longtime Oregon Health & Science University researcher has demonstrated in mice what could be a revolutionary new technique to cure a wide range of human diseases — from cystic fibrosis to cataracts to Alzheimer’s disease — that are caused by “misfolded” protein molecules. Misfolded protein molecules, caused by gene mutation,
OHSU AIDS vaccine candidate appears to completely clear virus from the body
Appears to have the ability to completely clear an AIDS-causing virus from the body An HIV/AIDS vaccine candidate developed by researchers at Oregon Health & Science University appears to have the ability to completely clear an AIDS-causing virus from the body. The promising vaccine candidate is being developed at OHSU’s Vaccine and Gene Therapy Institute. It is being
Now hear this: Scientists discover compound to prevent noise-related hearing loss
New research in The FASEB Journal suggests that excessive noise activates certain cells in the ear causing them to detach and damage the blood barrier Your mother was right when she warned you that loud music could damage your hearing, but now scientists have discovered exactly what gets damaged and how. In a research report
Human cloning developments raise hopes for new treatments
People with conditions such as heart disease or Parkinson’s could benefit from tissue grown with their own DNA Lorraine Barnes suffered a heart attack in 2005 and has lived with the consequences – extreme exhaustion and breathlessness – ever since. “I was separated from my husband and so my children, Charlotte and James, had to grow up
OHSU research team successfully converts human skin cells into embryonic stem cells
The breakthrough marks the first time human stem cells have been produced via nuclear transfer and follows several unsuccessful attempts by research groups worldwide Scientists at Oregon Health & Science University and the Oregon National Primate Research Center (ONPRC) have successfully reprogrammed human skin cells to become embryonic stem cells capable of transforming into any other cell
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