Francis Crick Institute

The Francis Crick Institute (formerly the UK Centre for Medical Research and Innovation) is a biomedical research centre in London, which was established in 2010 and opened in 2016

Using gene editing technology to create female-only and male-only mice litters with 100% efficiency

A new approach to treating pancreatic cancer

A protein that drives growth of pancreatic cancer, and which could be a target for new treatments, has been identified by researchers at the Crick. The study, published in Nature Cell Biology, looked into the most common type of pancreatic cancer, pancreatic ductal adenocarcinoma. This is an aggressive cancer that develops from secretory and tubular cells

A new approach to treating pancreatic cancer

A new AI-driven platform that can analyse how pathogens infect our cells with the precision of a trained biologist

New AI toolkit is the ‘scientist that never sleeps’ The platform, HRMAn (‘Herman’), which stands for Host Response to Microbe Analysis, is open-source, easy-to-use and can be tailored for different pathogens including Salmonella enterica. Pioneered by scientists at the Francis Crick Institute and UCL, HRMAn uses deep neural networks to analyse complex patterns in images of pathogen and human (‘host’)

A new AI-driven platform that can analyse how pathogens infect our cells with the precision of a trained biologist

AI can predict heart disease deaths better than doctors

A model developed using artificial intelligence (AI) is better at predicting risk of death in patients with heart disease than models designed by medical experts, a new study from the Francis Crick Institute shows. The study, published in PLOS One, adds to the growing evidence that AI could revolutionise healthcare in the UK and beyond. So far, the

AI can predict heart disease deaths better than doctors

Mapping electrical circuits in the brain far more comprehensively than ever before

Image: Model (left) and high resolution image (right) of the nanoengineered micropipette with holes to distribute electrical current. Credit: Daniel Schwarz In a feat of nanoengineering, scientists have developed a new technique to map electrical circuits in the brain far more comprehensively than ever before. In the brain, dedicated groups of neurons that connect up

Mapping electrical circuits in the brain far more comprehensively than ever before

Aspirin could hold the key to supercharged cancer immunotherapy

Giving cancer patients aspirin at the same time as immunotherapy could dramatically boost the effectiveness of the treatment, according to new research published in the journal Cell today (Thursday). Francis Crick Institute researchers, funded by Cancer Research UK, have shown that skin, breast and bowel cancer cells often produce large amounts of prostaglandin E2 (PGE2).

Aspirin could hold the key to supercharged cancer immunotherapy

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Nine UCL researchers secure £560m in research funding from ERC
Nine researchers from University College London (UCL) have secured nearly £560m in funding from the European Research Council’s (ERC) Advanced Grants to advance researchers in fields including ...
Looking at the environment around tumors could help predict how cancer spreads
according to new research led by UCL and the Francis Crick Institute. The study, published in Cancer Discovery and reported at the American Association for Cancer Research Annual Meeting 2024 ...
Cancer Research UK and CRIS fund lung cancer vaccine research
Cancer Research UK and the CRIS [Cancer Research ... grant to researchers at the University of Oxford, the Francis Crick Institute and University College London to develop the lung cancer vaccine ...
Researchers uncover protein interactions controlling fertility in female mice
Researchers at the Francis Crick Institute have shed light on the proteins ... of how female infertility develops. Following their research identifying the gene responsible for initiating the ...
The Francis Crick Institute
The Francis Crick Institute (formerly the UK Centre for Medical Research and Innovation) is a biomedical research centre in London, which opened in 2016. The institute is a partnership between ...

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Francis Crick Institute Discovery

Dr. Sam Barrell CBE appointed as CEO of LifeArc
Dr. Sam Barrell CBE appointed as CEO of LifeArc GlobeNewswire PRESS RELEASE FOR IMMEDIATE PUBLICATION 19 April 2024 LifeArc is pleased to announce the appointment of Dr. Sam Barrell, CBE, as Chief ...
Dr. Sam Barrell CBE appointed as CEO of LifeArc
Sam will join LifeArc from the Francis Crick Institute where she is currently ... accelerating the discovery of more innovative therapies and bringing real impact to the patients who need it ...
Study suggests tumour microenvironments could predict cancer progression
NSCLC is the most common type of lung cancer and is responsible for up to 85% of all cases Researchers from the Francis Crick Institute and University College ... The study was published in Cancer ...
Looking at the environment around tumors could help predict how cancer spreads
according to new research led by UCL and the Francis Crick Institute. The study, published in Cancer Discovery and reported at the American Association for Cancer Research Annual Meeting 2024 ...
Discovery of how COVID-19 virus replicates opens door to new antiviral therapies
A new paper led by Dr. Jeremy Carlton in collaboration with Dr. David Bauer at the Francis Crick Institute, focuses on how the Envelope protein of SARS-CoV-2 controls late stages of viral replication.

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The Francis Crick Institute (formerly the UK Centre for Medical Research and Innovation) is a biomedical research centre in London, which was established in 2010 and opened in 2016

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Francis Crick Institute Discovery

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