The map represents the city of Santiago de Cali as a network in which nodes represent its districts. The sizes of the nodes are proportional to the human population in each district, while the nodes are colored according to their importance for the release of Wolbachia-carrying mosquitoes. The links in the network represent mobility flows between Cali’s districts.
CREDIT: Adriana Reyna-Lara
Identifying vulnerable geographic areas so Wolbachia-carrying mosquitos can protect as many people as possible
Dengue is the most widespread mosquito-borne disease in the world, and to date, there are no medical treatments for people suffering from this disease. The virus causes symptoms ranging from high fevers to severe bleeding and shock, can be life-threatening, and presents an enormous burden on health systems.
In Chaos, by AIP Publishing, researchers from Spain, Portugal, and Colombia developed a model the virus. In 2009, researchers discovered mosquitoes carrying Wolbachia bacteria lessen the chances for the dengue virus to impact humans.
Mosquitoes do not acquire Wolbachia bacteria in their natural environment, however. This bacterium must be introduced in vitro in mosquitoes’ eggs, which are later released in areas affected by dengue transmission. Mosquitoes infected with Wolbachia naturally take over the local mosquito population.
The researchers use real data on human and vector activity in a framework that can be analyzed from a mathematical point of view, allowing them to re-create and understand the epidemiological situation. In this way, they can identify those geographical areas with the greatest vulnerability, creating a ranking of areas that prioritizes those where Wolbachia-carrying mosquitoes can have the strongest and most beneficial impact on the spread of the dengue virus.
“One might think that the most populated areas are those in which Wolbachia release would be most beneficial. However, this is not always true,” said co-author Jesus Gomez-Gardenes, from Universidad del Valle in Colombia.
The authors found once they immunize the most vulnerable geographical area, the ranking of the remaining areas is affected, giving rise to a new scenario that tells them where they should concentrate resources in the second instance and beyond.
The findings from this research will be beneficial to many groups, such as the World Mosquito Program, which is currently releasing Wolbachia-infected mosquitoes to protect the global community from diseases such as dengue, chikungunya, yellow fever, and Zika.
In these kinds of initiatives, the information about the most vulnerable areas within cities or regions proved the researchers’ model could complement field studies to find targets that maximize the benefit for the whole community.
“Data-driven models have also proven useful to tackle the evolution and mitigation of other diseases such as COVID-19,” said Gomez-Gardenes. “Hopefully, the framework developed for dengue can be further generalized for tackling the control of other vector-borne diseases.”
Original Article: Sending Out Bacteria-Carrying Mosquitoes to Protect People from Dengue
More from: University of Valle
The Latest on: Bacteria-carrying mosquitoes
- Do Mosquito-Repellent Plants Work? No—Here’s Why & What You Should Try Insteadon May 27, 2022 at 3:00 am
Place mosquito-repelling plants such as citronella, mint, lavender and lemon balm in beds or containers around your patio or garden , ...
- Climate change could trigger epidemics: malaria, dengue, zika, smallpox and pathogens from Siberian permafroston May 23, 2022 at 5:00 pm
The revival of ancient bacteria or viruses remains speculative ... whether by expanding the footprint of malaria- and dengue-carrying mosquitoes, or defrosting prehistoric pathogens from the ...
- “Biting Back Against Mosquitoes”on May 21, 2022 at 9:00 am
By County Executive Ed Day Mosquitoes are more than just a nuisance, they also spread dangerous diseases which is why, to help County residents reduce the number of mosquitoes on their property, my ...
- Ticks and mosquitoes: How bad will the season be and how to prevent biteson May 20, 2022 at 11:09 am
While mosquitos may present an itchy annoyance in most cases, some can carry West Nile virus or other ... Others say this year's tick and mosquito problems may be more mixed, or at least difficult ...
- New study suggests more malaria-carrying mosquito bites happen during the day than thoughton May 18, 2022 at 8:15 am
A team of researchers from Institut Pasteur de Bangui, the University of Montpellier and Centre International de Recherches Médicales de Franceville has found that contrary to conventional thought, ...
- Over three million 'tweaked' mosquitoes to be released in Johor as part pilot project to tackle dengueon May 18, 2022 at 4:59 am
More than three million eggs of the aedes mosquitoes carrying the Wolbachia strain will be released in a pilot project, to combat aedes mosquitoes, in the People's Housing Project (PPR) in Kempas here ...
- Johor: Over 3 mln aedes Wolbachia mosquitoes to be released in pilot project to reduce dengue caseson May 18, 2022 at 4:47 am
(It has been discovered that when aedes mosquitoes carrying Wolbachia, the bacteria with viruses such as dengue, zika, chikungunya and yellow fever, it makes it harder for viruses to reproduce inside ...
via Bing News
The Latest on: Bacteria-carrying mosquitoes
via Google News